Insulin Potentiation Therapy (IPT)
Insulin Potentiation Chemotherapy (IPT), also known as low dose chemotherapy, is one of the safest and most innovative approaches to treating cancer. It is a kinder, gentler way to fight cancer effectively, including particularly aggressive cancers such as lung cancer and colon cancer, but is also effective on a wide variety of cancer types. This alternative treatment has almost none of the side effects such as nausea, radical hair loss, liver damage, and DNA distortion that we see routinely with standard chemotherapy. The key to IPT as a cancer cure is the body's own hormone – insulin.
To learn more about IPT, please take a moment to view a presentation on this treatment prepared by Dr. Frank George. This presentation includes the advantages of insulin potentiation therapy, case studies, and an outline of the 4-fold approach to IPT taken by the doctors at EuroMed Foundation. You may also visit our FAQ page for answers to commonly asked questions about IPT.
Insulin manages the delivery of glucose across cell membranes into the cells. Cancer cells have 10-20 times more insulin receptors on their surface than normal cells. When insulin is released into the bloodstream by the pancreas in response to a meal, the insulin attaches to these receptors on the surface of the cell and, like a key fitting into a lock, opens channels in the cell wall to allow nutrients to go into the cell. Because cancer cells have more of these receptors, they compete for food better than normal cells. In this way, cancer cells thrive and normal cells are compromised.
To find out more about how the EuroMed Foundation uses IPT as a cancer cure, click here to request your free personal orientation online. One of our doctors will be happy to answer your basic questions in person or over the phone.
Sugar – The Sweet Spot for Cancer
You may have heard the expression, "sugar feeds cancer." Indeed it does. Yet at the same time, sugar is the Achilles heel of cancer.
PET scans for example find cancer by looking at the sugar uptake. The radioactive agent is mixed with sugar water and, because cancer cells take up much more sugar than normal cells, the radioactive agent congregates in the cancer cells. The resulting picture will indicate enhanced uptake and a mass where the cancer is.
We use that extreme need for sugar to our advantage with IPT when treating cancer. But instead of using a radioactive agent along with the sugar, we use chemotherapy. And we open the cellular membranes for significantly better absorption.
In IPT, we administer insulin to trigger a drop in the patient's blood sugar level. Healthy cells shift over to fat metabolism, but cancer cells rely almost entirely on sugar metabolism, so they go into an emergency mode and open all of their membranes in an effort to get the sugar they so desperately need. We have the cancer cells now in a very vulnerable position.
At this point, we administer a small amount of chemotherapy followed quickly by glucose (sugar). The cancer cells, in their desperate effort to get the glucose, take in almost the entire dose of chemotherapy drugs as well. The drugs poison and eventually kill the cancer cells.
How small a dose of drugs do we use? About one-tenth the amount of standard chemotherapy. That is why IPT is also known as low dose chemotherapy.
This method allows us to target the cytotoxic drugs directly to the cancer cell. There is little chemo left over to cause a toxic reaction within healthy cells. Patients who treat cancer with IPT have far fewer side effects.
In standard chemotherapy, insulin is not used to open the cells. Patients must be given a large dose of drugs so that enough will be absorbed by the cells to do the job. The majority of the drugs are not taken up by the cancer cells; the massive dosage wreaks havoc to healthy cells and blood components. Standard chemotherapy does not target cancer cells. The immune system takes a beating and patients experience many unpleasant side effects.
Insulin's Ability to Potentiate
The word "potentiate" means that one substance – insulin - enhances the effectiveness of another substance - chemotherapy - and thus far less drugs are needed.
Simply put, IPT consists of a pulse of hypoglycemia (low blood sugar) that improves the effectiveness of therapeutic drugs and supports health:
- IPT makes cell membranes more permeable, increasing the uptake of drugs into cells.
- IPT can help transport drugs across the blood-brain barrier.
- Insulin, in addition to its ability to help deliver higher-levels of the chemotherapy drugs into the cancer cells, also causes these cells to go into their growth phase where they actually become more vulnerable to the chemotherapy drugs. The cells are hit harder and at a time when they are most vulnerable to the assault, thus maximizing results.
- A 1981 study conducted at George Washington University showed that the chemo drug, methotrexate, when used with insulin, increased the drug's cell-killing effect by a factor of 10,000.
- Insulin assists debilitated cancer patients with appetite and metabolism, helping to mitigate the wasting – cachexia – that accompanies the disease and its therapy.
- IPT also may change the blood chemistry for the better. Dr. Perez Garcia studied this effect during IPT treatments and spoke of changes in the "biological terrane" of the body making it less hospitable to disease. He felt these changes persisted long after the treatment was over.
- IPT is believed to help detoxify. When the cell doors are open, things go in – and out. While IPT kills cancer cells, it flushes toxins into the circulation, enabling them to leave the body. This is why we pay special attention to supporting the liver during IPT.
- IPT's innovative approach was developed in the 1920s as an alternative to treating syphilis with almost lethal doses of mercury and arsenic. IPT was first used for cancer in 1945.
The practice of IPT is now worldwide. It is not yet taught in America's conventional medical schools, however. Medical school curriculum in the U.S. focuses mostly on insulin's role in diabetes. Pharmaceutical companies do not look favorably upon IPT because it uses so little of their product.
Diabetic patients need special attention and care. They can be treated by very experienced IPT physicians and with IPT using lower doses of insulin.
Having Low Dose Chemotherapy
Patients are asked to arrive the morning of their IPT appointments having fasted since dinner the night before. We want to clear the blood of glucose.
Patients make themselves comfortable in a private room, and an IV is inserted. Insulin is administered through the IV for about 20 to 40 minutes to drop the blood sugar. Normal blood glucose ranges from 80 to 100 mg/dl. During IPT we monitor it closely as it drops to perhaps 40 to 60 mg/dl.
After about 20 to 30 minutes, some patients will feel the symptoms of low blood sugar (mild hypoglycemia): hunger, thirst, drowsiness, mild sweat, increased body temperature, and faster heartbeat (tachycardia).
When the target number is reached, the "cell doors are open," and medications can be most effectively absorbed. Chemotherapy is added to the IV.
The administration of the drugs is rapidly followed by administration of concentrated glucose.
Symptoms of hypoglycemia will now rapidly disappear. In addition to the IV glucose, patients usually drink a high sugar beverage like fruit juice to restore normal blood sugar levels.
Total elapsed time for the IPT treatment typically ranges from 1 1/2 hours to 2 hours.
When patients first get started with IPT, doctors may schedule 1 or 2 sessions each week. Depending upon the severity of the cancer and the individual's reaction to therapy, IPT sessions will be eventually reduced to perhaps one a month, then one every three months. This is meant to be a general explanation to give you an idea of what to expect; patient protocols are developed on a case by case basis.
Your IPT sessions will very likely be interspersed with other complementary therapies that attack cancer cells, help your liver detoxify, and strengthen your immune system. One day, your body will be on its own again and we want to make it able to recognize cancer cells and aggressively attack them.
Another way in which our approach differs from the conventional oncologist's approach is that we do not use a "one size fits all" approach to medicines. We recognize that each person is unique, and each person will respond differently to different medicines. Insulin potentiation chemotherapy for an ovarian cancer patient will follow a different protocol than for a lung cancer patient or a breast cancer patient. IPT can be used to treat a wide variety of cancers.
If you've ever had a bladder infection for example, you may recall that your urine was tested against various antibiotics for sensitivity. The lab test determined which antibiotic would work best against your infection and your prescription was modified accordingly. We utilize a similar concept in customizing your IPT therapy.
We draw your blood and test your sensitivity to the universe of chemotherapy drugs, and to the universe of complementary homeopathic and natural substances we use to kill cancer, protect the liver during IPT, and rebuild the immune system. We want to know which chemotherapy drugs and which non-pharmaceutical remedies will work best for you. There is no need to subject your body unnecessarily to agents that will not perform well.
The most reliable lab we have found to do this test is in Greece, thus, we call it "the Greek test." We charge our patients only the actual cost of this test; we make no money on it. We feel it is that important and want to do all we can to encourage you to be tested.
IPT is a Holistic Approach
In the European tradition, we don't consider the job done simply when a marker shows zero (no metabolic activity). Whereas conventional cancer therapies tend to declare the cancer killed at that point and send you home to hope for the best, we know that a "clean test" is but one step in a bigger process. Healing is a process, one that Mother Nature tends to go about slowly, and in layers. Our goal is to eliminate the cancer you have, and, keep it from returning.
Thus our job – and your job – is not done when the PET Scan comes back "clean." The test shows the cancer is not detectable, but that does not mean there is no cancer. Our most successful patients keep a maintenance schedule to keep the cancer at that undetectable level while their bodies learn how to take control again.
As part of our commitment to holistic cancer treatment, we employ several treatment modalities as you progress in your cancer treatment. IPT is the primary weapon to stop the immediate danger by halting the growth of cancer quickly. Next, our other complementary therapies then become the primary weapons, creating cancer-hostile terrain in the body to protect you for the future and to retrain your body's ability to fight cancer on its own.
The treatment need not be worse than the disease. We think if everyone were aware of IPT, no one would choose standard chemotherapy and radiation. Our patients agree. IPT patients have much more energy and higher expectations for their recovery. Our IPT patients are able to devote more attention to their wellness, thus improving their quality of life.
If you would like to learn more about Insulin Potentiated Chemotherapy and alternative cancer treatment at the EuroMed Foundation, click here to request your free personal orientation online. Or you can call our office at 602-404-0400 to schedule a phone or in-person orientation.